Article
Genetic polymorphism of IL28B in hepatitis C-infected haemophilia patients in Israel.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jan 2013
Maor Y, Morali G, Bashari D, Pénaranda G, Schapiro J M, Martinowitz U, Halfon P
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) near the IL28B gene were identified as major predictors of treatment response (sustained virologic response--SVR) and spontaneous clearance of HCV. Haemophilia patients have the highest prevalence of HCV, and are a unique target for genetic studies. The Israeli population is ethnically heterogeneous; therefore, genetic variability is anticipated. To determine the IL28B...
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