Article
TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies.
Molecular psychiatry - 1 Jun 2011
Erhardt A, Czibere L, Roeske D, Lucae S, Unschuld P G, Ripke S, Specht M, Kohli M A, Kloiber S, Ising M, Heck A, Pfister H, Zimmermann P, Lieb R, Pütz B, Uhr M, Weber P, Deussing J M, Gonik M, Bunck M, Kebler M S, Frank E, Hohoff C, Domschke K, Krakowitzky P, Maier W, Bandelow B, Jacob C, Deckert J, Schreiber S, Strohmaier J, Nöthen M, Cichon S, Rietschel M, Bettecken T, Keck M E, Landgraf R, Müller-Myhsok B, Holsboer F, Binder E B
Abstract excerpt
The lifetime prevalence of panic disorder (PD) is up to 4% worldwide and there is substantial evidence that genetic factors contribute to the development of PD. Single-nucleotide polymorphisms (SNPs) in TMEM132D, identified in a whole-genome association study (GWAS), were found to be associated w...
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