Article
Genome wide assessment of young onset Parkinson's disease from Finland.
PloS one - 1 Jan 2012
Hernandez Dena G, Nalls Michael A, Ylikotila Pauli, Keller Margaux, Hardy John A, Majamaa Kari, Singleton Andrew B
Abstract excerpt
In the current study we undertook a series of experiments to test the hypothesis that a monogenic cause of disease may be detectable within a cohort of Finnish young onset Parkinson's disease patients. In the first instance we performed standard genome wide association analyses, and subsequent risk profile analysis. In addition we performed a series of analyses that involved testing measures of global relatedness...
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