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Article

Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivity.

PLoS pathogens - 1 Jan 2012

Ejigiri Ijeoma, Ragheb Daniel R T, Pino Paco, Coppi Alida, Bennett Brandy Lee, Soldati-Favre Dominique, Sinnis Photini

Abstract excerpt

Plasmodium sporozoites, the infective stage of the malaria parasite, move by gliding motility, a unique form of locomotion required for tissue migration and host cell invasion. TRAP, a transmembrane protein with extracellular adhesive domains and a cytoplasmic tail linked to the actomyosin motor,...

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Identifiers

PMID: 22911675
DOI: 10.1371/journal.ppat.1002725
PMCID: PMC3406075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22911675-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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