Article
Genetic polymorphisms in RNA binding proteins contribute to breast cancer survival.
International journal of cancer - 1 Feb 2013
Upadhyay Rohit, Sanduja Sandhya, Kaza Vimala, Dixon Dan A
Abstract excerpt
The RNA-binding proteins TTP and HuR control expression of numerous genes associated with breast cancer pathogenesis by regulating mRNA stability. However, the role of genetic variation in TTP (ZFP36) and HuR (ELAVL1) genes is unknown in breast cancer prognosis. A total of 251 breast cancer patie...
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