Article
hOGG1, p53 genes, and smoking interactions are associated with the development of lung cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Cheng Zhe, Wang Wei, Song Yong-Na, Kang Yan, Xia Jie
Abstract excerpt
This study aimed to investigate the effects of Ser/Cys polymorphism in hOGG1 gene, Arg/Pro polymorphism in p53 gene, smoking and their interactions on the development of lung cancer. Ser/Cys polymorphism in hOGG1 and Arg/Pro polymorphism in p53 among 124 patients with lung cancer and 128 normal people were detected using PCR-RFLP. At the same time, smoking status was investigated between the two groups. Logistic...
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