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Article

Abscission accomplished by PtdIns(3)P.

Nature cell biology - 1 Apr 2010

Montagnac Guillaume, Chavrier Philippe

Abstract excerpt

Cytokinesis - the final step of mitosis in which the two daughter cells separate - requires accumulation of specific proteins and lipids at the connecting bridge to ensure cleavage by abscission. Phosphatidylinositol-3-phosphate (PtdIns(3)P), an endosomal phosphoinositide, and FYVE-CENT, a PtdIns3P-binding protein, are found in the bridge, where they contribute to the mechanism of abscission.

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Identifiers

PMID: 20360746
DOI: 10.1038/ncb0410-308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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