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Article

Role of KCNMA1 in Breast Cancer

10 Aug 2012

Abstract excerpt

KCNMA1 encodes the α-subunit of the large conductance, voltage and Ca(2+)-activated (BK) potassium channel and has been reported as a target gene of genomic amplification at 10q22 in prostate cancer. To investigate the prevalence of the amplification in other human cancers, the copy number of KCNMA1 was analyzed by fluorescence-in-situ-hybridization (FISH) in 2,445 tumors across 118 different tumor types....

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PMID: 22899999
DOI: 10.1371/journal.pone.0041664

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