Article
ERCC1 C19007T polymorphism and the risk and invasiveness of cervical cancer in Korean women.
Asia-Pacific journal of clinical oncology - 1 Dec 2012
Han Seung-Su, Kim Jae Weon, Lee Sang Hoon, Kim Dong Ho, Park Noh-Hyun, Song Yong-Sang, Kang Soon-Beom
Abstract excerpt
AIM: Various DNA alterations by environmental or endogenous carcinogens, if not repaired, can cause genetic mutagenesis, resulting in carcinogenesis. A polymorphic variant of excision repair cross-complementation group 1 (ERCC1) (the DNA repair gene) may be associated with carcinogenesis due to reduced DNA repair capacity. The aim of this study was to investigate whether the ERCC1 C19007T polymorphism might be...
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