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Mapping differentiation pathways from hematopoietic stem cells using Flk2/Flt3 lineage tracing

24 Aug 2012

Abstract excerpt

Genetic fate-mapping approaches provide a unique opportunity to assess differentiation pathways under physiological conditions. We have recently employed a lineage tracing approach to define hematopoietic differentiation pathways in relation to expression of the tyrosine kinase receptor Flk2.1 Based on our examination of reporter activity across all stem, progenitor and mature populations in our Flk2-Cre lineage...

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PMID: 22895180
DOI: 10.4161/cc.21279

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