Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between the PRNP 1368 polymorphism and the occurrence of sporadic Creutzfeldt-Jakob disease.

Prion - 1 Jan 2000

Bratosiewicz-Wąsik Jolanta, Smoleń-Dzirba Joanna, Rozemuller Annemieke J, Jansen Casper, Spliet Wim, Jansen Gerard H, Wąsik Tomasz J, Liberski Paweł P

Abstract excerpt

Creutzfeldt-Jakob disease (CJD) is a rare transmissible neurodegenerative disorder. The etiology of sporadic form of CJD remains unsolved. In addition to the codon 129 polymorphism, polymorphisms in the non-coding region of PRNP are considered as important factors in sCJD development. To assess a possible association between PRNP 1368 SNP and sCJD, we compared the genotype, allele and haplotype frequencies of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Creutzfeldt-Jakob Syndrome
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PRNP gene

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Haplotypes

Share to Polymorphism, Single Nucleotide

Share to Prions

Source

Open in PubMed Open full text

Identifiers

PMID: 22895088
DOI: 10.4161/pri.21773
PMCID: PMC3609072

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between the PRNP 1368 polymorphism and the occurrence of sporadic Creutzfeldt-Jakob disease.PMID 22895088Read ↗

Association of the PRNP regulatory region polymorphisms with the occurrence of sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

PRNP 1368 polymorphism is not associated with sporadic Creutzfeldt-Jakob disease in the Korean population.Semantic proximity Read ↗

A polymorphism in the regulatory region of PRNP is associated with increased risk of sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

Lack of association between PRNP 1368 polymorphism and Alzheimer's disease or vascular dementia.Semantic proximity Read ↗

Significant association of a M129V independent polymorphism in the 5′ UTR of the <i>PRNP</i> gene with sporadic Creutzfeldt-Jakob disease in a large German case-control studySemantic proximity Read ↗

Codon 129 polymorphism of the PRNP gene in normal Polish population and in Creutzfeldt-Jakob disease, and the search for new mutations in PRNP gene.Semantic proximity Read ↗

The First Meta-Analysis of the M129V Single-Nucleotide Polymorphism (SNP) of the Prion Protein Gene (PRNP) with Sporadic Creutzfeldt-Jakob Disease.Semantic proximity Read ↗

Genetic risk factors associated with Creutzfeld-Jakob disease in Slovenians and a rapid typing for PRNP codon 129 single nucleotide polymorphism.Semantic proximity Read ↗

Genetic studies in human prion diseases.Semantic proximity Read ↗

PRNP variation in UK sporadic and variant Creutzfeldt Jakob disease highlights genetic risk factors and a novel non-synonymous polymorphism.Semantic proximity Read ↗

The influence of PRNP polymorphisms on human prion disease susceptibility: an update.Semantic proximity Read ↗

Regulatory sequences of the PRNP gene influence susceptibility to sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.