Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of cystic fibrosis transmembrane conductance regulator gene variants with acute lung injury in African American children with pneumonia*.

Critical care medicine - 1 Nov 2012

Baughn Julie M, Quasney Michael W, Simpson Pippa, Merchant Daniel, Li Shun-Hwa, Levy Hara, Dahmer Mary K

Abstract excerpt

OBJECTIVES: The cystic fibrosis transmembrane conductance regulator regulates fluid balance in alveolar epithelial cells and appears to modulate the inflammatory response. To determine whether more severe lung injury in children who develop community-acquired pneumonia is associated with variations known to affect function in the gene coding for cystic fibrosis transmembrane conductance regulator. DESIGN: A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lung Injury
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Community-Acquired Infections

Share to Cystic Fibrosis Transmembrane Conductance Regulator

Share to DNA Primers

Share to Infant

Share to Infant, Newborn

Share to Pneumonia

Source

Open in PubMed Open full text

Identifiers

PMID: 22890249
DOI: 10.1097/CCM.0b013e31825d8f73
PMCID: PMC4273667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of cystic fibrosis transmembrane conductance regulator gene variants with acute lung injury in African American children with pneumonia*.PMID 22890249Read ↗

The influence of genetic variation in surfactant protein B on severe lung injury in African American children.Semantic proximity Read ↗

Association of polymorphisms in genes of factors involved in regulation of splicing of cystic fibrosis transmembrane conductance regulator mRNA with acute respiratory distress syndrome in children with pneumonia.Semantic proximity Read ↗

Genetic variation in MYLK and lung injury in children and adults with community-acquired pneumonia.Semantic proximity Read ↗

DNA Sequencing Analysis of Cystic Fibrosis Transmembrane Regulator Gene Identifies Cystic Fibrosis-Associated Variants in the Severe Asthma Research Program.Semantic proximity Read ↗

Surfactant protein genetics in community-acquired pneumonia: balancing the host inflammatory state.Semantic proximity Read ↗

Non-invasive management of infants with SFTPC pathogenic variantsSemantic proximity Read ↗

Interleukin-1 receptor antagonist intron 2 variable number of tandem repeats polymorphism and respiratory failure in children with community-acquired pneumonia.Semantic proximity Read ↗

Genetic susceptibility to acute lung injury.Semantic proximity Read ↗

Correlation of METTL4 genetic variants and severe pneumonia pediatric patients in Southern China.Semantic proximity Read ↗

Cystic fibrosis transmembrane-conductance regulator mutations among African Americans.Semantic proximity Read ↗

Association between surfactant protein B + 1580 polymorphism and the risk of respiratory failure in adults with community-acquired pneumonia.Semantic proximity Read ↗

Cystic fibrosis modifier genes related to Pseudomonas aeruginosa infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.