Article
Association between surfactant protein B + 1580 polymorphism and the risk of respiratory failure in adults with community-acquired pneumonia.
Critical care medicine - 1 May 2004
Quasney Michael W, Waterer Grant W, Dahmer Mary K, Kron Grace K, Zhang Qing, Kessler Lori A, Wunderink Richard G
Abstract excerpt
OBJECTIVE: Pulmonary surfactant protein (SP)-B plays a vital role in the formation and function of surfactant in the lung. A genetic polymorphism (SP-B + 1580) is postulated to result in diminished activity of SP-B. The objective was to determine whether the SP-B + 1580 CC genotype is associated...
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