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Article

Implications of stress-induced genetic variation for minimizing multidrug resistance in bacteria.

BMC medicine - 13 Aug 2012

Obolski Uri, Hadany Lilach

Abstract excerpt

BACKGROUND: Antibiotic resistance in bacterial infections is a growing threat to public health. Recent evidence shows that when exposed to stressful conditions, some bacteria perform higher rates of horizontal gene transfer and mutation, and thus acquire antibiotic resistance more rapidly. METHODS: We incorporate this new notion into a mathematical model for the emergence of antibiotic multi-resistance in a...

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Share to Anti-Bacterial Agents
Share to Bacteria
Share to Bacterial Physiological Phenomena

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cross Infection

Share to Drug Resistance, Multiple, Bacterial

Share to Gene Transfer, Horizontal

Share to Hospitals

Share to Stress, Physiological

Source

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Identifiers

PMID: 22889082
DOI: 10.1186/1741-7015-10-89
PMCID: PMC3482572

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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