Article
[The glutathione peroxidase 1 (GPX1) single nucleotide polymorphism pro198Leu: association with life span and coronary artery disease].
Molekuliarnaia biologiia - 1 Jan 2000
Zeĭkova T V, Golubenko M V, Buĭkin S V, Botkina O Iu, Makeeva O A, Lezhnev A A, Kalianov E V, Tsimbaliuk I V, Maksimov V N, Voevoda M I, Shipulin V M, Puzyrev V P
Abstract excerpt
In this study we genotyped polymorphism in GPX1 Pro198Leu (C > T) rs 1050450 in four groups: patients with coronary artery disease, long-livers - above 90 years, early died peoples (before 55 years) from cardiovascular diseases and Russian population as control group. We have found significant higher allele T frequency in men with coronary artery disease -34.84% (Chi2 = 5.228, p = 0.022; OR = 1.46) and in early...
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