Article
Genetic characterization of a Chinese family with familial idiopathic pulmonary fibrosis.
Chinese medical journal - 1 Jun 2012
Zhang Xin, Jiang Jun, Chen Wei-Jun, Su Long-Xiang, Xie Li-Xin
Abstract excerpt
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic inflammatory interstitial lung disease with an unknown cause. Recent studies have shown that genetic factors play an important role in the pathogenesis of IPF. METHODS: To explore the genetic background of patients with IPF, a candidate gene approach was employed to screen for mutations in seven genes among members with familial IPF in mainland of...
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