Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A haplotype at STAT2 Introgressed from neanderthals and serves as a candidate of positive selection in Papua New Guinea.

American journal of human genetics - 10 Aug 2012

Mendez Fernando L, Watkins Joseph C, Hammer Michael F

Abstract excerpt

Signals of archaic admixture have been identified through comparisons of the draft Neanderthal and Denisova genomes with those of living humans. Studies of individual loci contributing to these genome-wide average signals are required for characterization of the introgression process and investigation of whether archaic variants conferred an adaptive advantage to the ancestors of contemporary human populations....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Biological
Share to Gene Components

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Linkage Disequilibrium

Share to Neanderthals

Share to Papua New Guinea

Share to Receptor, ErbB-3

Share to Selection, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 22883142
DOI: 10.1016/j.ajhg.2012.06.015
PMCID: PMC3415544

Genes

STAT2
ERBB3
ESYT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A haplotype at STAT2 Introgressed from neanderthals and serves as a candidate of positive selection in Papua New Guinea.PMID 22883142Read ↗

Neandertal origin of genetic variation at the cluster of OAS immunity genes.Semantic proximity Read ↗

Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes.Semantic proximity Read ↗

Denisovan introgression has shaped the immune system of present-day PapuansSemantic proximity Read ↗

A global map for introgressed structural variation and selection in humansSemantic proximity Read ↗

The shaping of modern human immune systems by multiregional admixture with archaic humans.Semantic proximity Read ↗

Adaptive variation in human toll-like receptors is contributed by introgression from both Neandertals and DenisovansSemantic proximity Read ↗

Introgression of Neandertal- and Denisovan-like Haplotypes Contributes to Adaptive Variation in Human Toll-like Receptors.Semantic proximity Read ↗

Archaic Hominin Admixture Facilitated Adaptation to Out-of-Africa Environments.Semantic proximity Read ↗

Neanderthal introgression at chromosome 3p21.31 was under positive natural selection in East Asians.Semantic proximity Read ↗

Immune context unmasks regulatory effects of Neanderthal and Denisovan introgressionSemantic proximity Read ↗

The contribution of Neanderthal introgression to modern human traits.Semantic proximity Read ↗

Impact and evolutionary determinants of Neanderthal introgression on transcriptional and post-transcriptional regulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.