Article
[Association between leptin gene promoter methylation and type 2 diabetes mellitus].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Aug 2012
Yang Mei, Sun Jia-zhong, Sun Yan-lei, You Wei, Dai Jing, Li Guang-sen
Abstract excerpt
OBJECTIVE: To assess the association between leptin gene promoter methylation and serum leptin concentrations in patients with impaired glucose regulation (IGR) and type 2 diabetes mellitus (T2DM). METHODS: Methylation status of leptin gene promoter was determined with methylation-specific polymerase chain reaction. Serum leptin concentrations were determined using enzyme-linked immunosorbent assay. RESULTS:...
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