Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential anaplerotic role for the energy-converting hydrogenase Eha in hydrogenotrophic methanogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 18 Sept 2012

Lie Thomas J, Costa Kyle C, Lupa Boguslaw, Korpole Suresh, Whitman William B, Leigh John A

Abstract excerpt

Despite decades of study, electron flow and energy conservation in methanogenic Archaea are still not thoroughly understood. For methanogens without cytochromes, flavin-based electron bifurcation has been proposed as an essential energy-conserving mechanism that couples exergonic and endergonic reactions of methanogenesis. However, an alternative hypothesis posits that the energy-converting hydrogenase Eha...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Electrons
Share to Ferredoxins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Formate Dehydrogenases

Share to Hydrogen

Share to Hydrogenase

Share to Methane

Share to Methanococcus

Share to Models, Chemical

Source

Open in PubMed Open full text

Identifiers

PMID: 22872868
DOI: 10.1073/pnas.1208779109
PMCID: PMC3458328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential anaplerotic role for the energy-converting hydrogenase Eha in hydrogenotrophic methanogenesis.PMID 22872868Read ↗

Hydrogenase-independent uptake and metabolism of electrons by the archaeon Methanococcus maripaludis.Semantic proximity Read ↗

Function and regulation of the formate dehydrogenase genes of the methanogenic archaeon Methanococcus maripaludis.Semantic proximity Read ↗

Characterization of energy-conserving hydrogenase B in Methanococcus maripaludis.Semantic proximity Read ↗

Genetic analysis of the archaeon Methanosarcina barkeri Fusaro reveals a central role for Ech hydrogenase and ferredoxin in methanogenesis and carbon fixation.Semantic proximity Read ↗

Hydrogen is a preferred intermediate in the energy-conserving electron transport chain of Methanosarcina barkeri.Semantic proximity Read ↗

Energy conservation by oxidation of formate to carbon dioxide and hydrogen via a sodium ion current in a hyperthermophilic archaeon.Semantic proximity Read ↗

The role of geochemistry and energetics in the evolution of modern respiratory complexes from a proton-reducing ancestor.Semantic proximity Read ↗

The Rnf Complex Is an Energy-Coupled Transhydrogenase Essential To Reversibly Link Cellular NADH and Ferredoxin Pools in the Acetogen Acetobacterium woodii.Semantic proximity Read ↗

Genetic, Biochemical, and Molecular Characterization of Methanosarcina barkeri Mutants Lacking Three Distinct Classes of Hydrogenase.Semantic proximity Read ↗

The microbial engines that drive Earth's biogeochemical cycles.Semantic proximity Read ↗

Heme biosynthesis is coupled to electron transport chains for energy generation.Semantic proximity Read ↗

Genome-scale metabolic reconstruction and hypothesis testing in the methanogenic archaeon Methanosarcina acetivorans C2A.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.