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Article

NDRG4, the N-Myc downstream regulated gene, is important for cell survival, tumor invasion and angiogenesis in meningiomas.

Integrative biology : quantitative biosciences from nano to macro - 1 Oct 2012

Kotipatruni Rama P, Ferraro Daniel J, Ren Xuan, Vanderwaal Robert P, Thotala Dinesh K, Hallahan Dennis E, Jaboin Jerry J

Abstract excerpt

Meningiomas are the second most common brain tumor, and 20-30% of these tumors are aggressive. The aggressive subtypes are characterized by a capacity for invasion of normal brain with frequent and destructive recurrence patterns. Effective local therapies include surgery and radiation, but there is a need for novel molecular targets to improve survival and reduce morbidity for this group or cancer patients. We...

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Identifiers

PMID: 22869042
DOI: 10.1039/c2ib20168b

Genes

NDRG4

Provenance

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NDRG4, the N-Myc downstream regulated gene, is important for cell survival, tumor invasion and angiogenesis in meningiomas.PMID 22869042Read ↗

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