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Article

N‐Myc downstream‐regulated gene 2 <i>(NDRG2)</i> inhibits glioblastoma cell proliferation

16 May 2003

Abstract excerpt

The most severe form of brain glioma, glioblastoma (GBM), is highly malignant and usually resistant to chemotherapy. Therefore, discovery of new targets for gene therapy is important. Using subtraction cloning, we identified the human N-Myc downstream-regulated gene 2 (hNDRG2), located at chromosome 14q11.2, as a gene that is significantly suppressed in GBM tissues. Semiquantitative RT-PCR showed that the hNDRG2...

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Cancer Mechanisms and Therapy
FOXO transcription factor regulation
Mechanisms of cancer metastasis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12845671
DOI: 10.1002/ijc.11228

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N‐Myc downstream‐regulated gene 2 <i>(NDRG2)</i> inhibits glioblastoma cell proliferationPMID 12845671Read ↗

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