Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries.

doi:10.1111/j.1582-4934.2012.01609.x

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Article

Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries.

Journal of cellular and molecular medicine - 1 Nov 2012

Harhun Maksym I, Huggins Christopher L, Ratnasingham Kumaran, Raje Durgesh, Moss Ray F, Szewczyk Kinga, Vasilikostas Georgios, Greenwood Iain A, Khong Teck K, Wan Andrew, Reddy Marcus

Abstract excerpt

Vascular interstitial cells (VICs) are non-contractile cells with filopodia previously described in healthy blood vessels of rodents and their function remains unknown. The objective of this study was to identify VICs in human arteries and to ascertain their role. VICs were identified in the wall of human gastro-omental arteries using transmission electron microscopy. Isolated VICs showed ability to form new and...

Topics

Actins
Arteries
Biomarkers
Calcium-Binding Proteins
Cytoskeleton
Female
Humans
Male
Microfilament Proteins
Microscopy, Electron, Transmission

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Muscle Proteins

Muscle, Smooth, Vascular

Myocytes, Smooth Muscle

Myosin-Light-Chain Kinase

Phenotype

Calponins

Source

Open in PubMed Open full text

Identifiers

PMID: 22862785
DOI: 10.1111/j.1582-4934.2012.01609.x
PMCID: PMC3492755

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