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Article

Impact of loading phase, initial response and CFH genotype on the long-term outcome of treatment for neovascular age-related macular degeneration.

PloS one - 1 Jan 2012

Menghini Moreno, Kloeckener-Gruissem Barbara, Fleischhauer Johannes, Kurz-Levin Malaika M, Sutter Florian K P, Berger Wolfgang, Barthelmes Daniel

Abstract excerpt

OBJECTIVE: Factors influencing the outcome of anti-VEGF treatment in neovascular AMD are still investigated. We analyzed the impact of a loading phase, the significance of an initial response for the long-term and the effect of the CFH polymorphism (p.His402Tyr) on treatment outcome. METHODS: Pat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22848690
DOI: 10.1371/journal.pone.0042014
PMCID: PMC3405003

Genes

CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22848690-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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