Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: a meta-analysis.

doi:10.1371/journal.pone.0042464

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Article

Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: a meta-analysis.

PloS one - 1 Jan 2012

Chen Han, Yu Ke-Da, Xu Ge-Zhi

Abstract excerpt

PURPOSE: To investigate the association between polymorphism rs1061170 (T1277C, Y402H) in age-related macular degeneration (AMD) susceptibility gene Complement Factor H (CFH) and treatment response of neovascular AMD. METHODS: We performed a literature-based meta-analysis including 10 published association studies involving 1,510 patients. Treatments included anti-VEGF (bevacizumab and ranibizumab) or...

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PMID: 22905135
DOI: 10.1371/journal.pone.0042464
PMCID: PMC3419212

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