Article
Insulin resistant phenotype of polycystic ovary syndrome does not seem to be caused by variation in FTO.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Oct 2012
Hatziagelaki E, Wagner R, Kantartzis K, Heni M, Linder K, Ketterer C, Machicao F, Stefan N, Staiger H, Häring H U, Fritsche A
Abstract excerpt
Genetic variation in the FTO gene is associated with increased body weight and reduced insulin sensitivity. We investigated whether genetic variation in FTO is associated with polycystic ovary syndrome (PCOS), a condition also characterized by insulin resistance. Furthermore, we tested whether insulin resistance is specifically associated with genetic variation in FTO in women with PCOS. Sixty-two nondiabetic...
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