Article
Cytokine genetic profile in Whipple's disease.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Nov 2012
Biagi F, Badulli C, Feurle G E, Müller C, Moos V, Schneider T, Marth T, Mytilineos J, Garlaschelli F, Marchese A, Trotta L, Bianchi P I, Di Stefano M, Cremaschi A L, De Silvestri A, Salvaneschi L, Martinetti M, Corazza G R
Abstract excerpt
Whipple's disease (WD) is a very rare chronic systemic condition characterised by a Th2/T regulatory (Treg) dysregulated immune response versus Tropheryma whipplei, a bacterium widely diffuse in the environment. To investigate whether this Th2/Treg polarised response has a genetic background, we investigated the Th1, Th2, Th17 and Treg cytokine genetic profile of 133 patients with WD. Thanks to the European...
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