Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Human Rhodopsin Kinase Promoter in an AAV5 Vector Confers Rod- and Cone-Specific Expression in the Primate Retina

30 Jul 2012

Abstract excerpt

Adeno-associated virus (AAV) has proven an effective gene delivery vehicle for the treatment of retinal disease. Ongoing clinical trials using a serotype 2 AAV vector to express RPE65 in the retinal pigment epithelium have proven safe and effective. While many proof-of-concept studies in animal models of retinal disease have suggested that gene transfer to the neural retina will also be effective, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Retinal and Optic Conditions
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22845794
DOI: 10.1089/hum.2012.125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Human Rhodopsin Kinase Promoter in an AAV5 Vector Confers Rod- and Cone-Specific Expression in the Primate RetinaPMID 22845794Read ↗

Adeno-Associated Virus Type 5: Transduction Efficiency and Cell-Type Specificity in the Primate RetinaSemantic proximity Read ↗

Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal deliverySemantic proximity Read ↗

Retinal transduction profiling of diverse AAV serotypes via intravitreal injectionSemantic proximity Read ↗

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retinaSemantic proximity Read ↗

Adeno-Associated Virus-Vectored Gene Therapy for Retinal DiseaseSemantic proximity Read ↗

Synthetic Adeno-Associated Viral Vector Efficiently Targets Mouse and Nonhuman Primate Retina In VivoSemantic proximity Read ↗

Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65Semantic proximity Read ↗

AAV8-vectored suprachoroidal gene transfer produces widespread ocular transgene expressionSemantic proximity Read ↗

Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach.Semantic proximity Read ↗

Adeno-associated virus vectors for retinal gene therapy in basic research and clinical studiesSemantic proximity Read ↗

Adeno-associated viral vectors for retinal gene transfer and treatment of retinal diseases.Semantic proximity Read ↗

Gene Therapy of Inherited Retinopathies: A Long and Successful Road from Viral Vectors to PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.