Article
Biomarkers in sepsis at time zero: intensive care unit scores, plasma measurements and polymorphisms in Argentina.
Journal of infection in developing countries - 23 Jul 2012
Perés Wingeyer Silvia Daniela Amanda, Cunto Eleonora Roxana, Nogueras Cristina Mabel, San Juan Jorge Alejandro, Gomez Norberto, de Larrañaga Gabriela Fernanda
Abstract excerpt
INTRODUCTION: A patient's response to sepsis is influenced by their genetic background. Our objective was to use plasma markers, such as protein C (PC), D-dimer, Plasminogen Activator Inhibitor-1 (PAI-1) levels, and the PAI-1 rs1799889 4G/5G and Tumor Necrosis Factor-α rs1800629 G/A polymorphisms to improve classical intensive care unit (ICU) scores. METHODOLOGY: We studied 380 subjects, 166 with sepsis. We...
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