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A comparative recombination analysis of human coronaviruses and implications for the SARS-CoV-2 pandemic

30 Aug 2021

Abstract excerpt

The SARS-CoV-2 pandemic prompts evaluation of recombination in human coronavirus (hCoV) evolution. We undertook recombination analyses of 158,118 public seasonal hCoV, SARS-CoV-1, SARS-CoV-2 and MERS-CoV genome sequences using the RDP4 software. We found moderate evidence for 8 SARS-CoV-2 recombination events, two of which involved the spike gene, and low evidence for one SARS-CoV-1 recombination event. Within...

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PMID: 34462471
DOI: 10.1038/s41598-021-96626-8

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