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Article

Genotype shift in human coronavirus OC43 and emergence of a novel genotype by natural recombination.

The Journal of infection - 1 Jun 2015

Zhang Yue, Li Jianguo, Xiao Yan, Zhang Jing, Wang Ying, Chen Lan, Paranhos-Baccalà Gláucia, Ren Lili, Wang Jianwei

Abstract excerpt

BACKGROUND: Human coronavirus (HCoV) OC43 is the most prevalent HCoV in respiratory tract infections. Its molecular epidemiological characterization, particularly the genotyping, was poorly addressed. METHODS: The full-length spike (S), RNA-dependent RNA polymerase (RdRp), and nucleocapsid (N) genes were amplified from each respiratory sample collected from 65 HCoV-OC43-positive patients between 2005 and 2012....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25530469
DOI: 10.1016/j.jinf.2014.12.005
PMCID: PMC7112537

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