Article
Identification and evolutionary dynamics of two novel human coronavirus OC43 genotypes associated with acute respiratory infections: phylogenetic, spatiotemporal and transmission network analyses.
Emerging microbes & infections - 4 Jan 2017
Oong Xiang Yong, Ng Kim Tien, Takebe Yutaka, Ng Liang Jie, Chan Kok Gan, Chook Jack Bee, Kamarulzaman Adeeba, Tee Kok Keng
Abstract excerpt
Human coronavirus OC43 (HCoV-OC43) is commonly associated with respiratory tract infections in humans, with five genetically distinct genotypes (A to E) described so far. In this study, we obtained the full-length genomes of HCoV-OC43 strains from two previously unrecognized lineages identified among patients presenting with severe upper respiratory tract symptoms in a cross-sectional molecular surveillance study...
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