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Article

Whole genome sequencing for lung cancer.

1 Apr 2012

Abstract excerpt

Lung cancer is a leading cause of cancer related morbidity and mortality globally, and carries a dismal prognosis. Improved understanding of the biology of cancer is required to improve patient outcomes. Next-generation sequencing (NGS) is a powerful tool for whole genome characterisation, enabling comprehensive examination of somatic mutations that drive oncogenesis. Most NGS methods are based on polymerase...

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PMID: 22833821
DOI: 10.3978/j.issn.2072-1439.2012.02.01

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