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Article

Genomic Profiling of Bronchoalveolar Lavage Fluid in Lung Cancer.

Cancer research - 16 Aug 2022

Nair Viswam S, Hui Angela Bik-Yu, Chabon Jacob J, Esfahani Mohammad S, Stehr Henning, Nabet Barzin Y, Zhou Li, Chaudhuri Aadel A, Benson Jalen, Ayers Kelsey, Bedi Harmeet, Ramsey Meghan, Van Wert Ryan, Antic Sanja, Lui Natalie, Backhus Leah, Berry Mark, Sung Arthur W, Massion Pierre P, Shrager Joseph B, Alizadeh Ash A, Diehn Maximilian

Abstract excerpt

Genomic profiling of bronchoalveolar lavage (BAL) samples may be useful for tumor profiling and diagnosis in the clinic. Here, we compared tumor-derived mutations detected in BAL samples from subjects with non-small cell lung cancer (NSCLC) to those detected in matched plasma samples. Cancer Personalized Profiling by Deep Sequencing (CAPP-Seq) was used to genotype DNA purified from BAL, plasma, and tumor samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35748739
DOI: 10.1158/0008-5472.CAN-22-0554
PMCID: PMC9379362

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