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Article

Comprehensive model of wild-type and mutant HIV-1 reverse transciptases.

Journal of computer-aided molecular design - 1 Aug 2012

Ballante Flavio, Musmuca Ira, Marshall Garland R, Ragno Rino

Abstract excerpt

An enhanced version of COMBINE that uses both ligand-based and structure-based alignment of ligands has been used to build a comprehensive 3-D QSAR model of wild-type HIV-1 reverse transcriptase and drug-resistant mutants. The COMBINEr model focused on 7 different RT enzymes complexed with just t...

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Identifiers

PMID: 22833004
DOI: 10.1007/s10822-012-9586-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22833004-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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