Multi-target QSAR modelling in the analysis and design of HIV-HCV co-inhibitors: an in-silico study

Abstract excerpt

BACKGROUND: HIV and HCV infections have become the leading global public-health threats. Even more remarkable, HIV-HCV co-infection is rapidly emerging as a major cause of morbidity and mortality throughout the world, due to the common rapid mutation characteristics of the two viruses as well as their similar complex influence to immunology system. Although considerable progresses have been made on the study of...

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