Article
Gene expression biomarkers of response to citalopram treatment in major depressive disorder.
Translational psychiatry - 21 Jun 2011
Mamdani F, Berlim M T, Beaulieu M-M, Labbe A, Merette C, Turecki G
Abstract excerpt
There is significant variability in antidepressant treatment outcome, with ∼30-40% of patients with major depressive disorder (MDD) not presenting with adequate response even following several trials. To identify potential biomarkers of response, we investigated peripheral gene expression patterns of response to antidepressant treatment in MDD. We did this using Affymetrix HG-U133 Plus2 microarrays in blood...
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