Article
Expression of podoplanin is a rare event in sporadic gastrointestinal stromal tumors and does not influence prognosis.
Future oncology (London, England) - 1 Jul 2012
Schoppmann Sebastian F, Berghoff Anna Sophie, Jesch Bettina, Zacherl Johannes, Nirtl Nadine, Jomrich Gerd, Maroske Florian, Streubel Berthold, Mesteri Ildiko, Birner Peter
Abstract excerpt
AIMS: Podoplanin overexpression is associated with worse prognosis in several human cancers. In gastrointestinal stromal tumors (GISTs) very few data on the expression of podoplanin exist, but it seems to be frequently overexpressed in pediatric/syndromic GISTs. We investigated podoplanin expression and its clinical relevance in a large series of sporadic GISTs. METHODS: Podoplanin expression was determined...
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