Inositol polyphosphate 5-phosphatases; new players in the regulation of cilia and ciliopathies.

doi:10.1016/j.febslet.2012.07.037

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Inositol polyphosphate 5-phosphatases; new players in the regulation of cilia and ciliopathies.

FEBS letters - 31 Aug 2012

Conduit Sarah E, Dyson Jennifer M, Mitchell Christina A

Abstract excerpt

Phosphoinositides regulate numerous cellular events via the recruitment and activation of multiple lipid-binding effector proteins. The precise temporal and spatial regulation of phosphoinositide signals by the co-ordinated activities of phosphoinositide kinases and phosphatases is essential for homeostasis and development. Mutations in two inositol polyphosphate 5-phosphatases, INPP5E and OCRL, cause the...

Topics

Cilia
Humans
Inositol Polyphosphate 5-Phosphatases
Mutation
Phosphatidylinositols
Phosphoric Monoester Hydrolases
Syndrome

Source

Open in PubMed

Identifiers

PMID: 22828281
DOI: 10.1016/j.febslet.2012.07.037

Genes

OCRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics