Article
A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients.
International journal of oncology - 1 Oct 2012
Dasgupta Santanu, Pal Prodipto, Mukhopadhyay Nitai D, Fu Yumei, Ratovitski Edward A, Moon Chul-So, Hoque Mohammad Obaidul, Fisher Paul B, Trink Barry
Abstract excerpt
Colorectal cancer (CRC) represents one of the highest incidences of cancers worldwide. Phosphatidylinositol glycan, class K (PIGK), is a crucial member of the glycosyl-phosphatidylinositol transamidase (GPIT) protein complex that attaches a diverse group of macromolecules to the plasma membrane of eukaryotes. However, the precise role of PIGK in tumorigenesis remains largely unknown. Recently, we reported low...
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