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Article

Premature coronary heart disease and autosomal dominant hypercholesterolemia: Increased risk in women with LDLR mutations.

Journal of clinical lipidology - 1 Jan 2000

Ahmad Zahid, Li Xilong, Wosik Jedrek, Mani Preethi, Petr Joye, McLeod George, Murad Shatha, Song Li, Adams-Huet Beverley, Garg Abhimanyu

Abstract excerpt

BACKGROUND: For patients with autosomal dominant hypercholesterolemia (ADH), it remains unclear whether differences exist in the risk of premature coronary heart disease (CHD) between patients with confirmed mutations in low-density lipoprotein receptor (LDLR) vs those without detectable mutations. OBJECTIVE: This study sought to assess the risk of premature CHD in ADH patients with mutations in LDLR (referred to...

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Share to Cholesterol, LDL
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

Share to Hyperlipoproteinemia Type II

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Share to Receptors, LDL

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Source

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Identifiers

PMID: 26892126
DOI: 10.1016/j.jacl.2015.09.003
PMCID: PMC4761103

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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