Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Wayward effect of polymorphism (TA)8 in the promoter region of UGT1A1 gene in a Mexican family.

The West Indian medical journal - 1 Jan 2012

Tintos-Hernández J A, Perea F J, Ibarra B, Figuera L E

Abstract excerpt

Gilbert syndrome (GS) is a hereditary relatively common benign unconjugated hyperbilirubinaemia. The promoter region of uridine diphosphate glycosyltransferase 1 (UGT1A1) gene contains a normal A (TA)6TAA element; variations in this motif (A(TA)7/8TAA) are generally associated with this disorder This is a report of the varied effects of GS in a Mexican Mestizo family with a non-common (TA)8 repeat in this...

Topics

Adult
Alleles
Female
Gilbert Disease
Glucuronosyltransferase
Humans
Polymorphism, Genetic
Promoter Regions, Genetic
Young Adult

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22808571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wayward effect of polymorphism (TA)8 in the promoter region of UGT1A1 gene in a Mexican family.PMID 22808571Read ↗

Frequency of the UGT1A1*28 Polymorphism in a Romanian Cohort of Gilbert Syndrome Individuals.Semantic proximity Read ↗

(TA)8 allele in the UGT1A1 gene promoter of a Caucasian with Gilbert's syndrome.Semantic proximity Read ↗

Frequencies of UDP-glucuronosyltransferase 1 (UGT1A1) gene promoter polymorphisms among distinct ethnic groups from Brazil.Semantic proximity Read ↗

Genotype frequencies of UDP-glucuronosyltransferase 1A1 promoter gene polymorphism in the population of healthy Croatian pre-scholars.Semantic proximity Read ↗

UGT1A1(TA)n promoter polymorphism--a new case of a (TA)8 allele in Caucasians.Semantic proximity Read ↗

[A study of polymorphism in UDP-glucuronosyltransferase 1 (UGT-1A1) promoter gene in Korean patients with Gilbert's syndrome].Semantic proximity Read ↗

[Distribution of the A(TA)7TAA genotype associated with Gilbert syndrome in the Spanish population].Semantic proximity Read ↗

Gilbert’s syndrome: High frequency of the (TA)7TAA allele in India and its interaction with a novel CAT insertion in promoter of the gene for bilirubin UDP-glucuronosyltransferase 1 geneSemantic proximity Read ↗

A new case of (TA)8 allele in the UGT1A1 gene promoter in a Caucasian girl with Gilbert syndrome.Semantic proximity Read ↗

Analysis of the A(TA)(n)TAA configuration in the promoter region of the UGT1 A1 gene in Greek patients with thalassemia intermedia and sickle cell disease.Semantic proximity Read ↗

Impact of UGT1A1 gene variants on total bilirubin levels in Gilbert syndrome patients and in healthy subjects.Semantic proximity Read ↗

Identification of Promotor and Exonic Variations, and Functional Characterization of a Splice Site Mutation in Indian Patients with Unconjugated Hyperbilirubinemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.