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Article

Apical left ventricular aneurysm without atrio-ventricular block due to a lamin A/C gene mutation.

European journal of heart failure - 1 Dec 2003

Forissier Jean-François, Bonne Gisèle, Bouchier Christiane, Duboscq-Bidot Laetitia, Richard Pascale, Wisnewski Claudine, Briault Sylvain, Moraine Claude, Dubourg Olivier, Schwartz Ketty, Komajda Michel

Abstract excerpt

BACKGROUND: Mutations in LMNA gene encoding two ubiquitously expressed nuclear proteins, lamins A and C, give rise to up to 7 different pathologies affecting specific tissues. Three of these disorders affect cardiac and/or skeletal muscles with atrio-ventricular conduction disturbances, dilated cardiomyopathy and sudden cardiac death as common features. RESULTS: A new LMNA mutation (1621C>T, R541C) was found in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14675861
DOI: 10.1016/s1388-9842(03)00149-1

Genes

LMNA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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