Article
Mutational analysis of the MTHFR gene in breast cancer patients of Pakistani population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Akram Muhammad, Malik F A, Kayani Mahmood Akhtar
Abstract excerpt
OBJECTIVES: Since methylenetetrahydrofolate reductase (MTHFR) maintains the balance of circulating folate and methionine and blocks the formation of homocysteine, its regulation in relation to different cancers has extensively been studied in different populations. However, information on Pakistani breast cancer patients is lacking. The MTHFR gene has two most common mutations that are single nucleotide additions...
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