Article
Nature versus nurture in frontotemporal lobar degeneration: the interaction of genetic background and education on brain damage.
Dementia and geriatric cognitive disorders - 1 Jan 2012
Premi E, Garibotto V, Alberici A, Paghera B, Giubbini R, Padovani A, Borroni B
Abstract excerpt
BACKGROUND: Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disorder with a strong genetic background. It has been reported that modifiable factors, i.e. education (E), might act as proxies for reserve capacity. OBJECTIVE: To evaluate the impact of genetic background (positive family history, FH) on reserve mechanisms, by measuring regional cerebral blood flow (rCBF) correlates in FTLD...
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