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High Education May Offer Protection Against Tauopathy in Patients with Mild Cognitive Impairment

8 Jul 2010

Abstract excerpt

The concepts of brain and cognitive reserve stem from the observation that premorbid factors (e.g., education) result in variation in the response to brain pathology. Potential early influence of reserve on pathology, as assessed using the cerebrospinal fluid biomarkers total tau (t-tau) and amyloid-beta42, and cognition was explored in mild cognitive impairment (MCI) patients who remained stable over a two-year...

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PMID: 20413900
DOI: 10.3233/jad-2010-091012

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