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Article

Development and evaluation of a line probe assay for rapid typing of influenza viruses and detection of the H274Y mutation.

Journal of virological methods - 1 Nov 2012

Miyoshi-Akiyama Tohru, Akasaka Yuki, Oogane Teruko, Kondo Yuji, Matsushita Takeji, Funatogawa Keiji, Kirikae Teruo

Abstract excerpt

Adequate treatment of influenza requires identification of viral type as well as detection of mutation(s) conferring drug resistance. Reverse hybridization-based line probe assays (LiPA) can be performed using several probes immobilized on nitrocellulose, strips enabling LiPA to determine simultaneously viral subtypes and detect the presence or absence of the H274Y mutation, which confers oseltamivir resistance...

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PMID: 22796550
DOI: 10.1016/j.jviromet.2012.06.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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