Article
Complete surgical resection of lung tumor decreases exhalation of mutated KRAS oncogene.
Respiratory medicine - 1 Sept 2012
Kordiak Jacek, Szemraj Janusz, Hamara Katarzyna, Bialasiewicz Piotr, Nowak Dariusz
Abstract excerpt
Exhaled breath condensate (EBC) contains extracellular DNA that may originate from pathological lesions of the respiratory tract and can be a genetic marker of pulmonary malignancy. We tested whether complete surgical excision of lung cancer will decrease exhalation of mutated KRAS oncogene. Fifty seven patients with clinical diagnosis of lung cancer and detectable KRAS mutations in pre-surgery EBC-DNA were...
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