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Article

Genetics of age-related white matter lesions from linkage to genome wide association studies.

Journal of the neurological sciences - 15 Nov 2012

Freudenberger Paul, Schmidt Reinhold, Schmidt Helena

Abstract excerpt

White matter lesions are a frequent phenomenon in the elderly and contribute to the development of disability. The mechanisms underlying these brain lesions are still not fully understood with age and hypertension being the most well established risk factors. The heritability of white matter lesions is consistently high in different populations. Candidate gene studies strongly support the role of genes involved...

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Identifiers

PMID: 22795385
DOI: 10.1016/j.jns.2012.06.016
PMCID: PMC3484396

Genes

TRIM47
TRIM65

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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