Article
Promotion of osteogenic cell response using quasicovalent immobilized fibronectin on titanium surfaces: introduction of a novel biomimetic layer system.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons - 1 Aug 2012
Gorbahn Miriam, Klein Marcus O, Lehnert Michael, Ziebart Thomas, Brüllmann Dan, Köper Ingo, Wagner Wilfried, Al-Nawas Bilal, Veith Michael
Abstract excerpt
PURPOSE: Despite the undeniable potential of cell adhesion molecules such as fibronectin to support osteogenic cell responses and consecutive dental implant healing, the most beneficial mode of application onto titanium implant surfaces still requires investigation. Unspecific fibronectin adsorption on titanium dioxide (TiO(2)) surfaces can result in low-loading, high-desorption rates and protein-metal...
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