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Article

Role for Peptidylarginine Deiminase Enzymes in Disease and Female Reproduction

1 Jan 2012

Abstract excerpt

The peptidylarginine deiminases (PADs) are a family of calcium-dependent enzymes that post-translationally convert positively charged arginine residues to neutrally charged citrulline in a process called citrullination. There are five PAD family members (PAD1-4 and 6), each with unique tissue distribution patterns and functional roles including: cellular differentiation, nerve growth, apoptosis, inflammation,...

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Identifiers

PMID: 22790870
DOI: 10.1262/jrd.2011-040

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